sap30l

ID

ZDB-GENE-030131-5287

Name

sap30-like

Symbol

sap30l Nomenclature History

Previous Names

wu:fa26a11
wu:fc10g12
wu:fe36f07
zgc:77367 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable several functions, including non-sequence-specific DNA binding activity, bending; phosphatidylinositol phosphate binding activity; and zinc ion binding activity. Acts upstream of or within heart looping. Predicted to be located in nucleolus. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including anterior neural rod; pectoral fin bud; pericardial region; pleuroperitoneal region; and trunk. Orthologous to human SAP30L (SAP30 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77367 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Teittinen et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sap30l Human Ortholog

No data available

Associated With sap30l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR025717	Histone deacetylase complex subunit SAP30 zinc-finger
Domain	IPR025718	Histone deacetylase complex subunit SAP30, Sin3 binding domain
Family	IPR024145	Histone deacetylase complex subunit SAP30/SAP30-like
Homologous_superfamily	IPR038291	SAP30, C-terminal domain superfamily