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ZIRC
ZFIN ID: ZDB-GENE-030131-5286
Gene Name: RNA polymerase I subunit A
Gene Symbol: polr1a    Nomenclature History

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Previous Names: fa26a03, sb:cb935, wu:fa26a03

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to contribute to RNA polymerase I activity. Involved in embryonic viscerocranium morphogenesis and neural crest cell development. Predicted to localize to the RNA polymerase I complex. Human ortholog(s) of this gene implicated in acrofacial dysostosis Cincinnati type. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pectoral fin musculature; and segmental plate. Orthologous to human POLR1A (RNA polymerase I subunit A).
Genome Resources: Alliance (1),  Gene:327078 (1),  Ensembl(GRCz11):ENSDARG00000098375 (1)
DISEASE ASSOCIATED WITH polr1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acrofacial dysostosis Cincinnati type Alliance Acrofacial dysostosis, Cincinnati type 616462
DISEASE ASSOCIATED WITH polr1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic viscerocranium morphogenesis (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA polr1a-201 (1)    Ensembl 5286
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM polr1a No data available
MARKER RELATIONSHIPS
polr1a Contained in: [BAC] CH73-87E17 (1) (order this), CH211-2M15 (1) (order this)
polr1a Encodes: [EST] cb935 (1) (order this), fa26a03
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:XM_001922804 (1)
Genomic GenBank:AL929267 (1) 175892 bp
Select Tool
Polypeptide UniProtKB:A0A0R4I9V4 (1) 1693 aa
Sequence Clusters UniGene:12641 (1)
Sequence Information (all 32)
ORTHOLOGY for polr1a ( Chr: 14 )
CITATIONS (33)