Gene
slc25a4
- ID
- ZDB-GENE-030131-5275
- Name
- solute carrier family 25 member 4
- Symbol
- slc25a4 Nomenclature History
- Previous Names
-
- fa22e07
- wu:fa22e07
- zgc:77591
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have ATP transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to integral component of membrane and mitochondrial inner membrane. Is expressed in cephalic musculature; hypaxial myotome region; musculature system; myotome; and somite. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77591 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 | Alliance | Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 2 | 609283 |
mitochondrial DNA depletion syndrome 12a | Alliance | Mitochondrial DNA depletion syndrome 12A (cardiomyopathic type) AD | 617184 |
mitochondrial DNA depletion syndrome 12b | Alliance | Mitochondrial DNA depletion syndrome 12B (cardiomyopathic type) AR | 615418 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | ADP/ATP carrier protein, eukaryotic type | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial substrate/solute carrier |
---|---|---|---|---|---|
UniProtKB:Q6NX10
|
298 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
slc25a4-201
(1)
|
Havana | 1434 nt |
Interactions and Pathways
No data available
Plasmids
No data available