Gene
eif2s1a
- ID
- ZDB-GENE-030131-526
- Name
- eukaryotic translation initiation factor 2, subunit 1 alpha a
- Symbol
- eif2s1a Nomenclature History
- Previous Names
-
- eif2s1l
- fb36a08
- wu:fb36a08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have ribosome binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to localize to several cellular components, including eukaryotic 48S preinitiation complex; eukaryotic translation initiation factor 2 complex; and eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56510 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003029 | S1 domain |
| Domain | IPR044126 | IF2a, S1-like domain |
| Family | IPR011488 | Translation initiation factor 2, alpha subunit |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR024054 | Translation initiation factor 2, alpha subunit, middle domain superfamily |
| Homologous_superfamily | IPR024055 | Translation initiation factor 2, alpha subunit, C-terminal |
Domain Details Per Protein
| Protein | Length | IF2a, S1-like domain | Nucleic acid-binding, OB-fold | S1 domain | Translation initiation factor 2, alpha subunit | Translation initiation factor 2, alpha subunit, C-terminal | Translation initiation factor 2, alpha subunit, middle domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZWD3
|
315 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif2s1a-201
(1)
|
Ensembl | 1,523 nt |
Interactions and Pathways
No data available
Plasmids
No data available