Gene
cox5ab
- ID
- ZDB-GENE-030131-5162
- Name
- cytochrome c oxidase subunit 5Ab
- Symbol
- cox5ab Nomenclature History
- Previous Names
-
- Cox5a2 (1)
- cox5a
- cb01f09
- mg:cb01f09
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Enables cytochrome-c oxidase activity. Acts upstream of or within embryonic organ development and spinal cord motor neuron differentiation. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX5A (cytochrome c oxidase subunit 5A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Baden et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 20 | Alliance | Mitochondrial complex IV deficiency, nuclear type 20 | 619064 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase, subunit Va/VI | Cytochrome c oxidase, subunit Va/VI superfamily |
|---|---|---|---|
|
UniProtKB:A0A0R4IVC8
|
138 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cox5ab-201
(1)
|
Ensembl | 673 nt |
Interactions and Pathways
No data available
Plasmids
No data available