Gene

tecrb

ID
ZDB-GENE-030131-5154
Name
trans-2,3-enoyl-CoA reductase b
Symbol
tecrb Nomenclature History
Previous Names
  • tecr
  • cb250 (1)
  • gpsn2
  • mg:db03b10
  • sb:cb250
  • wu:fj63b12
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable oxidoreductase activity. Predicted to be involved in very long-chain fatty acid biosynthetic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including digestive system; eye; forebrain; musculature system; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TECR (trans-2,3-enoyl-CoA reductase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tecrb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive non-syndromic intellectual disability Alliance Mental retardation, autosomal recessive 14 614020
Associated With tecrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
Family IPR039357 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Domain Details Per Protein
Protein Length 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase Ubiquitin-like domain superfamily
UniProtKB:Q7T390 308
UniProtKB:B8JM52 205
UniProtKB:B8JM55 181
UniProtKB:B8JM53 242
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations