Gene
cdk13
- ID
- ZDB-GENE-030131-4975
- Name
- cyclin dependent kinase 13
- Symbol
- cdk13 Nomenclature History
- Previous Names
-
- cdc2l5
- fi49c05
- wu:fe16d10
- wu:fi49c05
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in phosphorylation of RNA polymerase II C-terminal domain and positive regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in congenital heart defects, dysmorphic facial features, and intellectual developmental disorder; hepatocellular carcinoma; intellectual disability; and prostate carcinoma. Orthologous to human CDK13 (cyclin dependent kinase 13).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital heart defects, dysmorphic facial features, and intellectual developmental disorder | Alliance | Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder | 617360 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available