Gene
pif1
- ID
- ZDB-GENE-030131-4928
- Name
- PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
- Symbol
- pif1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable 5'-3' DNA helicase activity. Predicted to be involved in DNA recombination; DNA repair; and mitochondrial genome maintenance. Predicted to act upstream of or within DNA damage response and telomere maintenance. Predicted to be located in mitochondrion and nucleus. Is expressed in ectoderm; head; optic tectum; pectoral fin musculature; and proliferative region. Orthologous to human PIF1 (PIF1 5'-to-3' DNA helicase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb934 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR010285 | DNA helicase Pif1-like, DEAD-box helicase domain |
| Domain | IPR049163 | DNA helicase Pif1-like, 2B domain |
| Family | IPR048293 | DNA helicase PIF1/RRM3/pfh1 |
| Family | IPR051055 | PIF1 DNA helicase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | DNA helicase Pif1-like, 2B domain | DNA helicase Pif1-like, DEAD-box helicase domain | DNA helicase PIF1/RRM3/pfh1 | PIF1 DNA helicase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV90
|
639 |
Interactions and Pathways
No data available
Plasmids
No data available