Gene
myo15b
- ID
- ZDB-GENE-030131-4797
- Name
- myosin XVB
- Symbol
- myo15b Nomenclature History
- Previous Names
-
- si:dkeyp-67e6.5
- wu:fd60h05 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity; actin binding activity; and cytoskeletal motor activity. Predicted to be involved in system development. Located in cytoplasm and nucleus. Orthologous to human MYO15B (myosin XVB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choksi et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa22145 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa35341 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa35342 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa42073 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa44769 | Allele with one point mutation | Unknown | Unknown | ENU | |
| sa45468 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa45469 | Allele with one point mutation | Unknown | Splice Site | ENU |
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Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0AB32TFZ7 | InterPro | 2023 |
| UniProtKB:A0AB32TY86 | InterPro | 2023 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
myo15b-201
(1)
|
Ensembl | 5,445 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-67E6 | ZFIN Curated Data | |
| Encodes | EST | fd60h05 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068218688 (1) | 6715 nt | ||
| Genomic | GenBank:BX088589 (1) | 242558 nt | ||
| Polypeptide | UniProtKB:A0AB32TFZ7 (1) | 2023 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Choksi, S.P., Babu, D., Lau, D., Yu, X., Roy, S. (2014) Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Development (Cambridge, England). 141:3410-9
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