Gene
zgc:56622
- ID
- ZDB-GENE-030131-4758
- Name
- zgc:56622
- Symbol
- zgc:56622 Nomenclature History
- Previous Names
-
- fd58h08
- wu:fd58h08
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be active in cytosol. Is expressed in intestinal bulb. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to human AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56622 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldo-keto reductase | Aldo/keto reductase, conserved site | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZWA4
|
289 | ||||
|
UniProtKB:A0A8M2BH91
|
324 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zgc:56622-201
(1)
|
Ensembl | 1,511 nt |
Interactions and Pathways
No data available
Plasmids
No data available