Gene
plxna4
- ID
- ZDB-GENE-030131-4663
- Name
- plexin A4
- Symbol
- plxna4 Nomenclature History
- Previous Names
-
- wu:fd49b01
- wu:fe15f03
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have semaphorin receptor activity. Involved in axon guidance; axonal defasciculation; and morphogenesis of a branching structure. Predicted to localize to integral component of plasma membrane and semaphorin receptor complex. Is expressed in several structures, including basal plate midbrain region; nervous system; optic vesicle; presumptive neural retina; and trigeminal placode. Orthologous to human PLXNA4 (plexin A4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu2440 (16 images)
- eu1056 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from van der Klaauw et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR013548 | Plexin, cytoplasmic RasGAP domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR041019 | Plexin, TIG domain 1 |
| Domain | IPR041362 | Plexin, TIG domain 2 |
| Domain | IPR046800 | Plexin, cytoplasmic RhoGTPase-binding domain |
| Family | IPR031148 | Plexin family |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin, cytoplasmic RasGAP domain | Plexin, cytoplasmic RhoGTPase-binding domain | Plexin family | Plexin repeat | Plexin, TIG domain 1 | Plexin, TIG domain 2 | PSI domain | Rho GTPase activation protein | Sema domain | Sema domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DK42
|
1903 | ||||||||||||||
|
UniProtKB:Q6BEA0
|
1903 | ||||||||||||||
|
UniProtKB:T1ECS6
|
1903 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plxna4-201
(1)
|
Ensembl | 8,676 nt |
Interactions and Pathways
No data available
Plasmids
No data available