Gene
slc15a1b
- ID
- ZDB-GENE-030131-4661
- Name
- solute carrier family 15 member 1b
- Symbol
- slc15a1b Nomenclature History
- Previous Names
-
- PEPT1 (1)
- slc15a1
- fd47f07
- wu:fd47f07
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Enables neutral L-amino acid transmembrane transporter activity. Predicted to be involved in dipeptide import across plasma membrane. Predicted to act upstream of or within oligopeptide transport; protein transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in digestive system; immune system; and male organism. Orthologous to human SLC15A1 (solute carrier family 15 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 26 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63490 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | MFS transporter superfamily | Proton-dependent oligopeptide transporter family | PTR2 family proton/oligopeptide symporter, conserved site |
|---|---|---|---|---|---|
| UniProtKB:Q7SYE4 | InterPro | 718 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc15a1b-201
(1)
|
Ensembl | 2,631 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-217L18 | ZFIN Curated Data | |
| Encodes | EST | fd47f07 | ||
| Encodes | cDNA | MGC:63490 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_198064 (1) | 2637 nt | ||
| Genomic | GenBank:BX950176 (1) | 174329 nt | ||
| Polypeptide | UniProtKB:Q7SYE4 (1) | 718 aa |
- Hu, Y., Luo, Z., Wang, M., Wu, Z., Liu, Y., Cheng, Z., Sun, Y., Xiong, J.W., Tong, X., Zhu, Z., Zhang, B. (2024) Prox1a promotes liver growth and differentiation by repressing cdx1b expression and intestinal fate transition in zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 52(1):66-77
- Wei, X., Tan, X., Chen, Q., Jiang, Y., Wu, G., Ma, X., Fu, J., Li, Y., Gang, K., Yang, Q., Ni, R., He, J., Luo, L. (2023) Extensive jejunal injury is repaired by migration and transdifferentiation of ileal enterocytes in zebrafish. Cell Reports. 42:112660112660
- Ahi, E.P., Brunel, M., Tsakoumis, E., Chen, J., Schmitz, M. (2022) Appetite regulating genes in zebrafish gut; a gene expression study. PLoS One. 17:e0255201
- Ding, Q., Lu, C., Hao, Q., Zhang, Q., Yang, Y., Olsen, R.E., Ringo, E., Ran, C., Zhang, Z., Zhou, Z. (2022) Dietary Succinate Impacts the Nutritional Metabolism, Protein Succinylation and Gut Microbiota of Zebrafish. Frontiers in nutrition. 9:894278
- Li, Y.F., Cheng, T., Zhang, Y.J., Fu, X.X., Mo, J., Zhao, G.Q., Xue, M.G., Zhuo, D.H., Xing, Y.Y., Huang, Y., Sun, X.Z., Wang, D., Liu, X., Dong, Y., Zhu, X.S., He, F., Ma, J., Chen, D., Jin, X., Xu, P.F. (2022) Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1. PLoS Biology. 20:e3001856
- Ma, J., Shao, X., Geng, F., Liang, S., Yu, C., Zhang, R. (2022) Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress. iScience. 25:104957
- Yang, Y., Li, Y., Fu, J., Li, Y., Li, S., Ni, R., Yang, Q., Luo, L. (2022) Intestinal precursors avoid being misinduced to liver cells by activating Cdx-Wnt inhibition cascade. Proceedings of the National Academy of Sciences of the United States of America. 119:e2205110119
- Del Vecchio, G., Murashita, K., Verri, T., Gomes, A.S., Rønnestad, I. (2021) Leptin receptor-deficient (knockout) zebrafish: effects on nutrient acquisition. General and comparative endocrinology. 310:113832
- Meirelles, M.G., Nornberg, B.F., da Silveira, T.L.R., Kütter, M.T., Castro, C.G., Ramirez, J.R.B., Pedrosa, V., Romano, L.A., Marins, L.F. (2021) Growth Hormone Overexpression Induces Hyperphagia and Intestinal Morphophysiological Adaptations to Improve Nutrient Uptake in Zebrafish. Frontiers in Physiology. 12:723853
- Molinari, G.S., Wojno, M., McCracken, V.J., Kwasek, K. (2021) The use of dipeptide supplementation as a means of mitigating the negative effects of dietary soybean meal on Zebrafish Danio rerio. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 257:110958
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