Gene

jam3b

ID

ZDB-GENE-030131-441

Name

junctional adhesion molecule 3b

Symbol

jam3b Nomenclature History

Previous Names

jam3
jamc.1 (1)
jamc (1)
psr
sr:nyz155
wu:fb30h11 (1)
wu:fc08c06 (1)
wu:fc13e04 (1)
wu:fc25g11 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have protein heterodimerization activity and protein homodimerization activity. Involved in myoblast fusion. Predicted to localize to several cellular components, including bicellular tight junction; desmosome; and integral component of membrane. Is expressed in several structures, including cranium; musculature system; myoblast; nervous system; and somite. Orthologous to human JAM3 (junctional adhesion molecule 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

18 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d123 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 18 figures from 7 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With jam3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Hemorrhagic destruction of the brain, subependymal calcification, and cataracts	613730

Associated With jam3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042974	Junctional adhesion molecule C
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily