Gene
ppp1r13bb
- ID
- ZDB-GENE-030131-4327
- Name
- protein phosphatase 1, regulatory subunit 13Bb
- Symbol
- ppp1r13bb Nomenclature History
- Previous Names
-
- ppp1r13b
- fc90h02
- si:ch211-253p18.1
- wu:fc90h02
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable p53 binding activity. Predicted to act upstream of or within apoptotic process; negative regulation of cell cycle; and regulation of apoptotic process. Predicted to be active in nucleus. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa1183 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa37008 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa39275 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa43417 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| uab373 | Allele with one deletion | Unknown | Unknown | CRISPR |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR028319 | Apoptosis-stimulating of p53 protein 1, RA domain |
| Domain | IPR048942 | Apoptosis-stimulating of p53 protein 2-like, RA domain |
| Family | IPR047163 | Apoptosis-stimulating of p53 protein 1/2 |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Apoptosis-stimulating of p53 protein 1/2 | Apoptosis-stimulating of p53 protein 1, RA domain | Apoptosis-stimulating of p53 protein 2-like, RA domain | SH3 domain | SH3-like domain superfamily | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AKR4 | InterPro | 1155 | ||||||||
| UniProtKB:A0A0R4IUG8 | InterPro | 1119 | ||||||||
| UniProtKB:A0A8M3AT48 | InterPro | 1163 | ||||||||
| UniProtKB:A5D6T8 | InterPro | 1069 | ||||||||
| UniProtKB:A0A8M3ALG4 | InterPro | 1051 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1r13bb-201
(1)
|
Ensembl | 4,511 nt | ||
| mRNA |
ppp1r13bb-203
(1)
|
Ensembl | 5,158 nt | ||
| mRNA |
ppp1r13bb-204
(1)
|
Ensembl | 4,928 nt | ||
| mRNA |
ppp1r13bb-205
(1)
|
Ensembl | 5,981 nt | ||
| mRNA |
ppp1r13bb-206
(1)
|
Ensembl | 5,519 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-253P18 | ZFIN Curated Data | |
| Contained in | BAC | CH211-271J4 | ZFIN Curated Data | |
| Encodes | EST | fc90h02 | ||
| Encodes | cDNA | MGC:162804 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001044824 (1) | 4555 nt | ||
| Genomic | GenBank:BX088722 (1) | 195359 nt | ||
| Polypeptide | UniProtKB:A0A8M3AT48 (1) | 1163 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Luo, D., Hu, W., Chen, S., Xiao, Y., Sun, Y., and Zhu, Z. (2009) Identification of Differentially Expressed Genes Between Cloned and Zygote-Developing Zebrafish (Danio rerio) Embryos at the Dome Stage Using Suppression Subtractive Hybridization. Biology of reproduction. 80(4):674-684
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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