tmem63ba

ID

ZDB-GENE-030131-4320

Name

transmembrane protein 63Ba

Symbol

tmem63ba Nomenclature History

Previous Names

fc90d11
wu:fc90d11

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable calcium-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to be located in endomembrane system and membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 118. Orthologous to human TMEM63B (transmembrane protein 63B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmem63ba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 118	Alliance	Developmental and epileptic encephalopathy 118	621250

Associated With tmem63ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003864	CSC1/OSCA1-like, 7TM region
Domain	IPR027815	CSC1/OSCA1-like, cytosolic domain
Domain	IPR032880	CSC1/OSCA1-like, N-terminal transmembrane domain
Family	IPR045122	Calcium permeable stress-gated cation channel 1-like
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily