Gene
pof1b
- ID
- ZDB-GENE-030131-4287
- Name
- POF1B actin binding protein
- Symbol
- pof1b Nomenclature History
- Previous Names
-
- fc88b11
- si:dkeyp-8h9.2
- wu:fa99b01
- wu:fc88b11 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; bicellular tight junction assembly; and epithelial cell morphogenesis. Predicted to be active in actin filament; adherens junction; and bicellular tight junction. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 2B. Orthologous to human POF1B (POF1B actin binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ovarian insufficiency 2B | Alliance | ?Premature ovarian failure 2B | 300604 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | POF1B, helix-loop-helix domain | Protein POF1B |
|---|---|---|---|---|
| UniProtKB:A0A8M9PDM7 | InterPro | 592 | ||
| UniProtKB:A0A2R8PYS8 | InterPro | 592 | ||
| UniProtKB:A0AB32TCG3 | InterPro | 515 | ||
| UniProtKB:A0AB32TP57 | InterPro | 515 | ||
| UniProtKB:A0AB40E7W1 | InterPro | 516 |
Interactions and Pathways
No data available
Plasmids
No data available