Gene
pde4cb
- ID
- ZDB-GENE-030131-4075
- Name
- phosphodiesterase 4C, cAMP-specific b
- Symbol
- pde4cb Nomenclature History
- Previous Names
-
- fc68c05
- si:ch211-255d18.1
- wu:fc68c05
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cAMP-mediated signaling. Predicted to act upstream of or within signal transduction. Orthologous to human PDE4C (phosphodiesterase 4C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1105 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023174 | 3'5'-cyclic nucleotide phosphodiesterase, conserved site |
| Domain | IPR002073 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
| Domain | IPR003607 | HD/PDEase domain |
| Domain | IPR040844 | Phosphodiesterase 4 upstream conserved regions (UCR) |
| Family | IPR023088 | 3'5'-cyclic nucleotide phosphodiesterase |
| Homologous_superfamily | IPR036971 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | 3'5'-cyclic nucleotide phosphodiesterase | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | HD/PDEase domain | Phosphodiesterase 4 upstream conserved regions (UCR) |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QHV8 | InterPro | 693 | ||||||
| UniProtKB:A0A8M9Q7G4 | InterPro | 670 | ||||||
| UniProtKB:A0A0R4IMH2 | InterPro | 680 | ||||||
| UniProtKB:A0A8M9QLT1 | InterPro | 721 | ||||||
| UniProtKB:A0AB32U285 | InterPro | 723 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pde4cb-201
(1)
|
Ensembl | 2,548 nt | ||
| mRNA |
pde4cb-202
(1)
|
Ensembl | 2,966 nt | ||
| mRNA |
pde4cb-203
(1)
|
Ensembl | 2,043 nt | ||
| mRNA |
pde4cb-204
(1)
|
Ensembl | 2,040 nt | ||
| mRNA |
pde4cb-205
(1)
|
Ensembl | 2,082 nt |
Interactions and Pathways
No data available
Plasmids
No data available