Gene
gspt1l
- ID
- ZDB-GENE-030131-4009
- Name
- G1 to S phase transition 1, like
- Symbol
- gspt1l Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity and translation release factor activity. Acts upstream of or within vasculature development. Predicted to be part of translation release factor complex. Is expressed in digestive system; head; hindbrain; proliferative region; and somite. Orthologous to human GSPT1 (G1 to S phase transition 1) and GSPT2 (G1 to S phase transition 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139179 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Wang et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR031157 | Tr-type G domain, conserved site |
| Domain | IPR000795 | Translational (tr)-type GTP-binding domain |
| Domain | IPR004161 | Translation elongation factor EFTu-like, domain 2 |
| Domain | IPR054696 | GTP-eEF1A, C-terminal domain |
| Family | IPR050100 | Translation factor GTPase superfamily members |
| Homologous_superfamily | IPR009000 | Translation protein, beta-barrel domain superfamily |
| Homologous_superfamily | IPR009001 | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | GTP-eEF1A, C-terminal domain | P-loop containing nucleoside triphosphate hydrolase | Translational (tr)-type GTP-binding domain | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Translation elongation factor EFTu-like, domain 2 | Translation factor GTPase superfamily members | Translation protein, beta-barrel domain superfamily | Tr-type G domain, conserved site |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T358 | InterPro | 577 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gspt1l-201
(1)
|
Ensembl | 2,558 nt | ||
| mRNA |
gspt1l-202
(1)
|
Ensembl | 764 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al. (2005. Genome Res. 15:1307-1914.) reported orthology to GSPT1 supported by amino acid sequence identity. Subsequent data supported that a different gene (ZDB-GENE-040822-36) is the ortholog of human GSPT1 based on higher amino acid sequence identity as well as conserved location.