Gene
rab18a
- ID
- ZDB-GENE-030131-3980
- Name
- RAB18A, member RAS oncogene family
- Symbol
- rab18a Nomenclature History
- Previous Names
-
- fc62e07
- wu:fc62e07
- zgc:77145
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity. Acts upstream of or within chordate embryonic development and eye development. Predicted to be located in apical plasma membrane and lipid droplet. Predicted to be active in Golgi apparatus. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907938 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bem et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Warburg micro syndrome 3 | Alliance | Warburg micro syndrome 3 | 614222 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rab | Sigma-54 interaction domain, ATP-binding site 1 | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6P129
|
205 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rab18a-202
(1)
|
Ensembl | 791 nt | ||
| mRNA |
rab18a-201
(1)
|
Ensembl | 2,335 nt |
Interactions and Pathways
No data available
Plasmids