Gene
rab18a
- ID
- ZDB-GENE-030131-3980
- Name
- RAB18A, member RAS oncogene family
- Symbol
- rab18a Nomenclature History
- Previous Names
-
- fc62e07
- wu:fc62e07
- zgc:77145
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have GTPase activity. Involved in chordate embryonic development and eye development. Predicted to localize to Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907938 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Bem et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Warburg micro syndrome 3 | Alliance | Warburg micro syndrome 3 | 614222 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Sigma-54 interaction domain, ATP-binding site 1 | Small GTPase | Small GTP-binding protein domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6P129
|
205 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| aberrant processed transcript |
rab18a-202
(1)
|
Havana | 791 nt | |
| mRNA |
rab18a-201
(1)
|
Havana | 2335 nt |
Interactions and Pathways
No data available
Plasmids