Gene
tp53bp1
- ID
- ZDB-GENE-030131-3695
- Name
- tumor protein p53 binding protein, 1
- Symbol
- tp53bp1 Nomenclature History
- Previous Names
-
- wu:fc50a09
- wu:fj67d04
- zgc:158452
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have histone binding activity. Predicted to be involved in DNA damage checkpoint and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human TP53BP1 (tumor protein p53 binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Yang et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001357 | BRCT domain |
| Domain | IPR015125 | Tumour suppressor p53-binding protein-1 Tudor domain |
| Domain | IPR047249 | TP53-binding protein 1-like, first BRCT domain |
| Domain | IPR047250 | TP53-binding protein 1-like, second BRCT domain |
| Family | IPR047252 | TP53-binding protein 1-like |
| Homologous_superfamily | IPR014722 | Large ribosomal subunit protein uL2, domain 2 |
| Homologous_superfamily | IPR036420 | BRCT domain superfamily |
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | Large ribosomal subunit protein uL2, domain 2 | TP53-binding protein 1-like | TP53-binding protein 1-like, first BRCT domain | TP53-binding protein 1-like, second BRCT domain | Tumour suppressor p53-binding protein-1 Tudor domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z753
|
1762 | |||||||
|
UniProtKB:A1L1W2
|
1709 | |||||||
|
UniProtKB:A0A8M6Z7P8
|
1499 | |||||||
|
UniProtKB:A0A8M6Z1I8
|
1642 | |||||||
|
UniProtKB:A0A8M6YZZ7
|
1754 | |||||||
|
UniProtKB:A0A8M9PNZ2
|
1636 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tp53bp1-201
(1)
|
Ensembl | 5,546 nt |
Interactions and Pathways
No data available
Plasmids
No data available