Gene

adgrg1

ID
ZDB-GENE-030131-3671
Name
adhesion G protein-coupled receptor G1
Symbol
adgrg1 Nomenclature History
Previous Names
  • fc49b10
  • gpr56
  • wu:fc49b10
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity. Involved in glial cell development and regulation of oligodendrocyte progenitor proliferation. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including heart; liver; nervous system; pleuroperitoneal region; and trigeminal placode. Orthologous to human ADGRG1 (adhesion G protein-coupled receptor G1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgrg1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
bilateral frontoparietal polymicrogyria Alliance Polymicrogyria, bilateral frontoparietal 606854
bilateral perisylvian polymicrogyria Alliance Polymicrogyria, bilateral perisylvian 615752
Associated With adgrg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000203 GPS motif
Domain IPR000719 Protein kinase domain
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001315 CARD domain
Domain IPR017981 GPCR, family 2-like
Family IPR000832 GPCR, family 2, secretin-like
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length CARD domain Death-like domain superfamily GPCR, family 2-like GPCR, family 2, secretin-like GPS motif Protein kinase domain Protein kinase-like domain superfamily Serine-threonine/tyrosine-protein kinase, catalytic domain
UniProtKB:A0A1D5NSB4 513
UniProtKB:F1QZM9 648
UniProtKB:Q59I63 648
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations