Gene
magt1
- ID
- ZDB-GENE-030131-3667
- Name
- magnesium transporter 1
- Symbol
- magt1 Nomenclature History
- Previous Names
-
- fc49b02
- wu:fc49b02
- zgc:56218 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable magnesium ion transmembrane transporter activity. Acts upstream of or within magnesium ion transport. Predicted to be located in endoplasmic reticulum and plasma membrane. Predicted to be part of oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; congenital disorder of glycosylation Icc; and non-syndromic X-linked intellectual disability. Orthologous to human MAGT1 (magnesium transporter 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56218 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Icc | Alliance | Congenital disorder of glycosylation, type Icc | 301031 |
| X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia | Alliance | Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia | 300853 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Oligosaccharyl transferase complex, subunit OST3/OST6 | Thioredoxin-like superfamily |
|---|---|---|---|
|
UniProtKB:Q7ZV50
|
328 |
Interactions and Pathways
No data available
Plasmids
No data available