Gene

sp8b

ID
ZDB-GENE-030131-3654
Name
sp8 transcription factor b
Symbol
sp8b Nomenclature History
Previous Names
  • sp8l
  • fc48e06
  • wu:fc48e06
  • zgc:77258
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Enables double-stranded DNA binding activity. Involved in embryonic limb morphogenesis. Acts upstream of or within embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to be located in nucleus. Is expressed in several structures, including apical ectodermal ridge pelvic fin bud; midbrain neural keel; nervous system; neural plate; and neural tube. Orthologous to human SP8 (Sp8 transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa22810Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-sp8bN/A (2)
MO2-sp8bN/A (2)
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Human Disease
Associated With sp8b Human Ortholog
No data available
Associated With sp8b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
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Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:Q3L0W2 455
UniProtKB:Q6P0J3 437
UniProtKB:A0A8M9P7R9 437
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sp8b-201 (1) Ensembl 1,765 nt
mRNA sp8b-202 (1) Ensembl 2,045 nt
mRNA sp8b-203 (1) Ensembl 875 nt
mRNA sp8b-204 (1) Ensembl 1,704 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-226D12ZFIN Curated Data
Contained inBACCH211-180P9ZFIN Curated Data
EncodesESTfc48e06
EncodesESTwz1241
    ZFIN Curated Data
    EncodescDNAMGC:77258ZFIN Curated Data
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    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanSP87
    Conserved genome location (synteny) (2)
    Amino acid sequence comparison (2)
    MouseSp812
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    1 - 10 of 17
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