Gene
ptprna
- ID
- ZDB-GENE-030131-3511
- Name
- protein tyrosine phosphatase receptor type Na
- Symbol
- ptprna Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in insulin secretion involved in cellular response to glucose stimulus and regulation of secretion. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in transport vesicle membrane. Predicted to be active in secretory granule and synapse. Is expressed in brain. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PTPRN (protein tyrosine phosphatase receptor type N).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR021613 | Protein-tyrosine phosphatase receptor IA-2 ectodomain |
| Domain | IPR029403 | RESP18 domain |
| Family | IPR033522 | Receptor-type tyrosine-protein phosphatase-like N/N2 |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR038112 | Protein-tyrosine phosphatase receptor IA-2, ectodomain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Protein-tyrosine phosphatase receptor IA-2 ectodomain | Protein-tyrosine phosphatase receptor IA-2, ectodomain superfamily | Receptor-type tyrosine-protein phosphatase-like N/N2 | RESP18 domain | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z8D6 | InterPro | 902 | |||||||||
| UniProtKB:F1R8X1 | InterPro | 903 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptprna-201
(1)
|
Ensembl | 3,619 nt | ||
| ncRNA |
ptprna-002
(1)
|
Ensembl | 1,444 nt |
Interactions and Pathways
No data available
Plasmids
No data available