Gene

mylk3

ID
ZDB-GENE-030131-3497
Name
myosin light chain kinase 3
Symbol
mylk3 Nomenclature History
Previous Names
  • mlck (1)
  • cardiac-MLCK (1)
  • fc41h03
  • si:rp71-34g2.1
  • wu:fc41h03 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have myosin light chain kinase activity. Involved in heart morphogenesis; sarcomerogenesis; and ventricular cardiac myofibril assembly. Predicted to localize to cytoplasm. Is expressed in lens; notochord; pericardial region; and somite. Orthologous to human MYLK3 (myosin light chain kinase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Seguchi et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mylk3 Human Ortholog
No data available
Associated With mylk3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A8C984 715
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mylk3-201 (1) Ensembl 3,212 nt
mRNA mylk3-202 (1) Ensembl 3,708 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations