ZFIN is now using GRCz12tu for Genomic Data
Gene
dlg5a
- ID
- ZDB-GENE-030131-3149
- Name
- discs, large homolog 5a (Drosophila)
- Symbol
- dlg5a Nomenclature History
- Previous Names
-
- dlg5 (1)
- wu:fc28f03
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in negative regulation of hippo signaling. Orthologous to human DLG5 (discs large MAGUK scaffold protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Yuksel-Vogel-Bauser syndrome | 620703 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR006907 | Disks large homolog 5, N-terminal |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR035537 | Disks large homologue 5, SH3 domain |
| Family | IPR053004 | MAGUK Family Regulators of Signaling Pathways |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | CARD domain | Death-like domain superfamily | Disks large homolog 5, N-terminal | Disks large homologue 5, SH3 domain | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | MAGUK Family Regulators of Signaling Pathways | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3BEL3 | InterPro | 1957 | ||||||||||||
| UniProtKB:A0A8M2B3K9 | InterPro | 1961 | ||||||||||||
| UniProtKB:B7ZC95 | InterPro | 1926 | ||||||||||||
| UniProtKB:E7EXQ0 | InterPro | 1958 | ||||||||||||
| UniProtKB:A0A8M9QJT2 | InterPro | 1413 | ||||||||||||
| UniProtKB:A0AB32T3B5 | InterPro | 1987 | ||||||||||||
| UniProtKB:A0AB32T3F8 | InterPro | 1984 | ||||||||||||
| UniProtKB:A0AB32T4Q0 | InterPro | 1983 |
Interactions and Pathways
No data available
Plasmids
No data available