Gene
hmga2
- ID
- ZDB-GENE-030131-3148
- Name
- high mobility group AT-hook 2
- Symbol
- hmga2 Nomenclature History
- Previous Names
-
- wu:fc27f12
- wu:fc28f02
- wu:fc57d12
- zgc:77719
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable transcription coregulator activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in several structures, including blood vessel; head; nervous system; pectoral fin bud; and pronephric duct. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; leiomyoma; lipoma; and ovarian cancer. Orthologous to human HMGA2 (high mobility group AT-hook 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77719 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Wang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Silver-Russell syndrome 5 | 618908 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AT hook, DNA-binding motif | High mobility group protein HMGA | HMG-I/HMG-Y, DNA-binding, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q6P038
|
110 |
Interactions and Pathways
No data available
Plasmids
No data available