Gene
dpysl5a
- ID
- ZDB-GENE-030131-3136
- Name
- dihydropyrimidinase like 5a
- Symbol
- dpysl5a Nomenclature History
- Previous Names
-
- CRMP-5a (1)
- fc28b06
- im:7146614
- wu:fc28b06
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in nervous system; spinal cord neural tube; and trigeminal placode. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome. Orthologous to human DPYSL5 (dihydropyrimidinase like 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146614 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ritscher-Schinzel syndrome 4 | 619435 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006680 | Amidohydrolase-related |
| Family | IPR011778 | Hydantoinase/dihydropyrimidinase |
| Family | IPR050378 | Metallo-dependent Hydrolases Superfamily |
| Homologous_superfamily | IPR011059 | Metal-dependent hydrolase, composite domain superfamily |
| Homologous_superfamily | IPR032466 | Metal-dependent hydrolase |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Amidohydrolase-related | Hydantoinase/dihydropyrimidinase | Metal-dependent hydrolase | Metal-dependent hydrolase, composite domain superfamily | Metallo-dependent Hydrolases Superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q52PJ7 | InterPro | 564 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dpysl5a-201
(1)
|
Ensembl | 4,408 nt | ||
| mRNA |
dpysl5a-202
(1)
|
Ensembl | 3,509 nt | ||
| mRNA |
dpysl5a-203
(1)
|
Ensembl | 1,715 nt | ||
| mRNA |
dpysl5a-204
(1)
|
Ensembl | 4,486 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-77G5 | ZFIN Curated Data | |
| Encodes | EST | fc28b06 | ||
| Encodes | EST | IMAGE:7146614 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:153833 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192401 | ZFIN Curated Data |
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