Gene
pan2
- ID
- ZDB-GENE-030131-3113
- Name
- poly(A) specific ribonuclease subunit PAN2
- Symbol
- pan2 Nomenclature History
- Previous Names
-
- fc27e10
- si:dkey-126g1.10
- wu:fc27e10 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable exonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of PAN complex. Predicted to be active in P-body. Orthologous to human PAN2 (poly(A) specific ribonuclease subunit PAN2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013520 | Exonuclease, RNase T/DNA polymerase III |
| Domain | IPR028881 | PAN2, UCH domain |
| Domain | IPR028889 | Ubiquitin specific protease domain |
| Domain | IPR048841 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2, N-terminal |
| Family | IPR030843 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 |
| Family | IPR050785 | PAN2-PAN3 complex catalytic subunit |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Exonuclease, RNase T/DNA polymerase III | PAN2-PAN3 complex catalytic subunit | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2, N-terminal | PAN2, UCH domain | Papain-like cysteine peptidase superfamily | Ribonuclease H-like superfamily | Ribonuclease H superfamily | Ubiquitin specific protease domain | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B989
|
1206 | |||||||||||
|
UniProtKB:E9QJN4
|
1202 |
Interactions and Pathways
No data available
Plasmids
No data available