Gene

fkbp10b

ID

ZDB-GENE-030131-3101

Name

FKBP prolyl isomerase 10b

Symbol

fkbp10b Nomenclature History

Previous Names

fkbp10
wu:fc27c03

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity and peptidyl-prolyl cis-trans isomerase activity. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Is expressed in several structures, including ball; ectoderm; median fin fold; splanchnocranium; and vasculature. Orthologous to human FKBP10 (FKBP prolyl isomerase 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6894076 (13 images)
IMAGE:6897831 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fkbp10b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Bruck syndrome	Alliance	Bruck syndrome 1	259450
osteogenesis imperfecta type 11	Alliance	Osteogenesis imperfecta, type XI	610968

Associated With fkbp10b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR001179	FKBP-type peptidyl-prolyl cis-trans isomerase domain
Domain	IPR002048	EF-hand domain
Family	IPR051989	FK506-binding protein-like isomerase
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR046357	Peptidyl-prolyl cis-trans isomerase domain superfamily