Gene

cyp3c1

ID
ZDB-GENE-030131-3060
Name
cytochrome P450, family 3, subfamily c, polypeptide 1
Symbol
cyp3c1 Nomenclature History
Previous Names
  • CYP3A (1)
  • wu:fa96d12
  • wu:fc26b04
  • zgc:56626
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Enables heme binding activity. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including digestive system; heart; integument; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp3c1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Vitamin D-dependent rickets, type 3 619073
1 - 1 of 1
Associated With cyp3c1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR050705 Cytochrome P450 3A
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length Cytochrome P450 Cytochrome P450 3A Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:Q7ZTW6 InterPro 505
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cyp3c1-201 (1)
Ensembl
Ensembl 1,931 nt
ZFIN BLAST
mRNA cyp3c1-202 (1)
Ensembl
Ensembl 617 nt
ZFIN BLAST
mRNA cyp3c1-203 (1)
Ensembl
Ensembl 530 nt
ZFIN BLAST
mRNA cyp3c1-204 (1)
Ensembl
Ensembl 1,741 nt
ZFIN BLAST
1 - 4 of 4
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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