Gene
fanci
- ID
- ZDB-GENE-030131-2905
- Name
- FA complementation group I
- Symbol
- fanci Nomenclature History
- Previous Names
-
- fc21c10
- wu:fc21c10
- zgc:152941
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have DNA polymerase binding activity. Predicted to be involved in DNA repair. Human ortholog(s) of this gene implicated in Fanconi anemia and Fanconi anemia complementation group I. Is expressed in central nervous system; head; heart; pectoral fin; and rostral blood island. Orthologous to human FANCI (FA complementation group I).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Titus et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ramanagoudr-Bhojappa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group I | Alliance | Fanconi anemia, complementation group I | 609053 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR029305 | FANCI solenoid 1 cap |
| Domain | IPR029308 | FANCI solenoid 1 domain |
| Domain | IPR029310 | FANCI helical domain 1 |
| Domain | IPR029312 | FANCI helical domain 2 |
| Domain | IPR029313 | FANCI solenoid 3 domain |
| Domain | IPR029314 | FANCI solenoid 4 domain |
| Domain | IPR029315 | FANCI solenoid 2 domain |
| Family | IPR026171 | Fanconi anemia group I protein |
Domain Details Per Protein
| Protein | Length | FANCI helical domain 1 | FANCI helical domain 2 | FANCI solenoid 1 cap | FANCI solenoid 1 domain | FANCI solenoid 2 domain | FANCI solenoid 3 domain | FANCI solenoid 4 domain | Fanconi anemia group I protein |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUU2
|
1376 | ||||||||
|
UniProtKB:F1R3B9
|
1327 |
Interactions and Pathways
No data available
Plasmids
No data available