Gene
puf60a
- ID
- ZDB-GENE-030131-2891
- Name
- poly-U binding splicing factor a
- Symbol
- puf60a Nomenclature History
- Previous Names
-
- fc21a05
- wu:fc21a05 (1)
- wu:fi43a08
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome; mRNA splice site selection; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Is expressed in central nervous system and pharynx. Orthologous to human PUF60 (poly(U) binding splicing factor 60).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from Rauch et al., 2003
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Verheij syndrome | 615583 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR003954 | RNA recognition motif domain, eukaryote |
| Domain | IPR034209 | PUF60, RNA recognition motif 1 |
| Domain | IPR034211 | PUF60, RNA recognition motif 2 |
| Domain | IPR034212 | PUF60, RNA recognition motif 3 |
| Family | IPR006532 | Poly-U binding splicing factor, PUF60-like |
| Family | IPR051974 | Poly(U)-binding-splicing regulator |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | Poly-U binding splicing factor, PUF60-like | Poly(U)-binding-splicing regulator | PUF60, RNA recognition motif 1 | PUF60, RNA recognition motif 2 | PUF60, RNA recognition motif 3 | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BAZ4
|
550 | |||||||||
|
UniProtKB:F1QZ57
|
552 | |||||||||
|
UniProtKB:A0A8M2BAV4
|
288 | |||||||||
|
UniProtKB:A0A8M9QNK1
|
352 | |||||||||
|
UniProtKB:A0A2R8QFM1
|
538 | |||||||||
|
UniProtKB:A0A8M9Q9Z9
|
371 | |||||||||
|
UniProtKB:A0A8M2BAQ4
|
533 | |||||||||
|
UniProtKB:A8E4R7
|
518 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
puf60a-201
(1)
|
Ensembl | 5,284 nt | ||
| mRNA |
puf60a-202
(1)
|
Ensembl | 930 nt | ||
| mRNA |
puf60a-204
(1)
|
Ensembl | 795 nt | ||
| mRNA |
puf60a-205
(1)
|
Ensembl | 1,095 nt | ||
| mRNA |
puf60a-206
(1)
|
Ensembl | 866 nt | ||
| mRNA |
puf60a-208
(1)
|
Ensembl | 769 nt | ||
| mRNA |
puf60a-209
(1)
|
Ensembl | 842 nt | ||
| mRNA |
puf60a-210
(1)
|
Ensembl | 2,188 nt | ||
| mRNA |
puf60a-212
(1)
|
Ensembl | 901 nt | ||
| mRNA |
puf60a-213
(1)
|
Ensembl | 5,310 nt | ||
| mRNA |
puf60a-214
(1)
|
Ensembl | 5,320 nt | ||
| mRNA |
puf60a-215
(1)
|
Ensembl | 5,430 nt | ||
| ncRNA |
puf60a-007
(1)
|
Ensembl | 807 nt | ||
| ncRNA |
puf60a-008
(1)
|
Ensembl | 879 nt | ||
| ncRNA |
puf60a-009
(1)
|
Ensembl | 630 nt |
Interactions and Pathways
No data available
Plasmids
No data available