Gene
myom1a
- ID
- ZDB-GENE-030131-2856
- Name
- myomesin 1a (skelemin)
- Symbol
- myom1a Nomenclature History
- Previous Names
-
- myom1
- im:7139709
- wu:fc19g07
- wu:fj97c07
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable kinase binding activity. Predicted to be involved in sarcomere organization. Predicted to be active in M band. Is expressed in musculature system; pectoral fin; and somite. Orthologous to human MYOM1 (myomesin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139709 (7 images)
- IMAGE:7160758 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa25832 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa25833 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa32946 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa38338 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa39849 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Striated Muscle Structural and Regulatory Protein |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M1NUG4 | InterPro | 1483 | |||||||||
UniProtKB:A0A8M2BAV8 | InterPro | 1459 |
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- Genome Browsers
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
myom1a-203
(1)
|
Ensembl | 5,891 nt | ||
mRNA |
myom1a-205
(1)
|
Ensembl | 748 nt | ||
ncRNA |
myom1a-002
(1)
|
Ensembl | 415 nt | ||
ncRNA |
myom1a-004
(1)
|
Ensembl | 924 nt | ||
ncRNA |
myom1a-005
(1)
|
Ensembl | 614 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
- Prill, K., Carlisle, C., Stannard, M., Windsor Reid, P.J., Pilgrim, D.B. (2019) Myomesin is part of an integrity pathway that responds to sarcomere damage and disease. PLoS One. 14:e0224206
- Zhang, L., Yang, Y., Li, B., Scott, I.C., Lou, X. (2018) The DEAD box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish. Development (Cambridge, England). 145(8)
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Nesan, D., and Vijayan, M.M. (2013) The transcriptomics of glucocorticoid receptor signaling in developing zebrafish. PLoS One. 8(11):e80726
- Sundström, G., Dreborg, S., and Larhammar, D. (2010) Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. PLoS One. 5(5):e10512
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Woods, I.G., Kelly, P.D., Chu, F., Ngo-Hazelett, P., Yan, Y.-L., Huang, H., Postlethwait, J.H., and Talbot, W.S. (2000) A comparative map of the zebrafish genome. Genome research. 10(12):1903-1914
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