Gene
stag2b
- ID
- ZDB-GENE-030131-2785
- Name
- STAG2 cohesin complex component b
- Symbol
- stag2b Nomenclature History
- Previous Names
-
- fc17g12
- wu:fc17g12 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have chromatin binding activity. Predicted to be involved in sister chromatid cohesion. Predicted to localize to chromatin; cohesin complex; and nucleus. Human ortholog(s) of this gene implicated in premature ovarian failure. Orthologous to several human genes including STAG2 (stromal antigen 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Ketharnathan et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Holoprosencephaly 13, X-linked | Alliance | Holoprosencephaly 13, X-linked | 301043 |
| Mullegama-Klein-Martinez syndrome | Alliance | Mullegama-Klein-Martinez syndrome | 301022 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | Cohesin subunit Scc3/SA | STAG | Stromalin conservative domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IZR5
|
1276 | ||||
|
UniProtKB:E7FE97
|
1269 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stag2b-201
(1)
|
Ensembl | 3,810 nt | ||
| mRNA |
stag2b-202
(1)
|
Ensembl | 1,055 nt | ||
| mRNA |
stag2b-203
(1)
|
Ensembl | 748 nt | ||
| mRNA |
stag2b-204
(1)
|
Ensembl | 6,646 nt | ||
| mRNA |
stag2b-206
(1)
|
Ensembl | 3,831 nt | ||
| ncRNA |
stag2b-003
(1)
|
Ensembl | 705 nt |
Interactions and Pathways
No data available
Plasmids
No data available