Gene
bcar1
- ID
- ZDB-GENE-030131-2774
- Name
- BCAR1 scaffold protein, Cas family member
- Symbol
- bcar1 Nomenclature History
- Previous Names
-
- fc17f11
- wu:fc17f11 (1)
- zgc:175192
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to be involved in actin filament reorganization; cell migration; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in breast ductal carcinoma. Orthologous to human BCAR1 (BCAR1 scaffold protein, Cas family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from O'Hare et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Wisniewski et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR014928 | Serine rich protein interaction domain |
| Domain | IPR021901 | CAS family, C-terminal |
| Domain | IPR035745 | BCAR1, SH3 domain |
| Family | IPR037362 | CAS family |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR038319 | CAS, serine rich four helix bundle domain superfamily |
Domain Details Per Protein
| Protein | Length | BCAR1, SH3 domain | CAS family | CAS family, C-terminal | CAS, serine rich four helix bundle domain superfamily | Serine rich protein interaction domain | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QJQ5
|
919 | |||||||
|
UniProtKB:A0A2R8Q9D0
|
946 | |||||||
|
UniProtKB:A0A8M9PM80
|
961 | |||||||
|
UniProtKB:B5DE36
|
919 |
Interactions and Pathways
No data available
Plasmids
No data available