Gene
prpf19
- ID
- ZDB-GENE-030131-263
- Name
- pre-mRNA processing factor 19
- Symbol
- prpf19 Nomenclature History
- Previous Names
-
- prp19
- fb18f09
- wu:fb18f09
- zgc:56158 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin-protein transferase activity. Acts upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator. Predicted to be located in nucleoplasm. Predicted to be part of Prp19 complex and U2-type catalytic step 1 spliceosome. Predicted to be active in cytoplasm. Orthologous to human PRPF19 (pre-mRNA processing factor 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909798 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR003613 | U-box domain |
| Family | IPR038959 | Pre-mRNA-processing factor 19 |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | Pre-mRNA-processing factor 19 | U-box domain | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV92
|
505 |
Interactions and Pathways
No data available
Plasmids
No data available