ZFIN is now using GRCz12tu for Genomic Data
Gene
rgs12a
- ID
- ZDB-GENE-030131-2614
- Name
- regulator of G protein signaling 12a
- Symbol
- rgs12a Nomenclature History
- Previous Names
-
- fc13d03
- wu:fc13d03 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Orthologous to human RGS12 (regulator of G protein signaling 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003109 | GoLoco motif |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR003116 | Raf-like Ras-binding |
| Domain | IPR006020 | PTB/PI domain |
| Domain | IPR016137 | RGS domain |
| Family | IPR046995 | Regulator of G-protein signaling 10/12/14-like |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR024066 | RGS, subdomain 1/3 |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
Domain Details Per Protein
| Protein | Additional Resources | Length | GoLoco motif | PDZ domain | PDZ superfamily | PH-like domain superfamily | PTB/PI domain | Raf-like Ras-binding | Regulator of G-protein signaling 10/12/14-like | RGS domain | RGS domain superfamily | RGS, subdomain 1/3 | RGS, subdomain 2 | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QV08 | InterPro | 1370 | ||||||||||||
| UniProtKB:A0A8N7URF2 | InterPro | 1371 | ||||||||||||
| UniProtKB:A0A8M2BJJ9 | InterPro | 750 | ||||||||||||
| UniProtKB:A0A8M3B3Z7 | InterPro | 1370 | ||||||||||||
| UniProtKB:A0A8M3B127 | InterPro | 770 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rgs12a-201
(1)
|
Ensembl | 4,638 nt | ||
| mRNA |
rgs12a-202
(1)
|
Ensembl | 838 nt | ||
| mRNA |
rgs12a-203
(1)
|
Ensembl | 4,733 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers