plekhg6

ID

ZDB-GENE-030131-2517

Name

pleckstrin homology domain containing, family G (with RhoGef domain) member 6

Symbol

plekhg6 Nomenclature History

Previous Names

fc10d07
si:ch211-215m13.2
wu:fc10d07 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in angiogenesis and endothelial cell migration. Predicted to be active in endocytic vesicle and plasma membrane. Orthologous to human PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plekhg6 Human Ortholog

No data available

Associated With plekhg6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000219	Dbl homology domain
Domain	IPR001849	Pleckstrin homology domain
Family	IPR040181	Pleckstrin homology domain-containing family G member 5/7
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily