Gene

hspb8

ID
ZDB-GENE-030131-2480
Name
heat shock protein b8
Symbol
hspb8 Nomenclature History
Previous Names
  • fc09c11
  • wu:fc04b04
  • wu:fc09c11
  • zgc:64202
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is expressed in several structures, including cephalic musculature; immature eye; midbrain hindbrain boundary neural rod; nervous system; and pericardial region. Orthologous to human HSPB8 (heat shock protein family B (small) member 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hspb8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease axonal type 2L Alliance Charcot-Marie-Tooth disease, axonal, type 2L 608673
distal hereditary motor neuronopathy type 2A Alliance Neuronopathy, distal hereditary motor, type IIA 158590
Associated With hspb8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002068 Alpha crystallin/Hsp20 domain
Domain IPR042790 Heat shock protein beta-8, alpha-crystallin domain (ACD)
Family IPR001436 Alpha crystallin/Small heat shock protein, animal type
Family IPR043254 Heat shock protein beta-8
Homologous_superfamily IPR008978 HSP20-like chaperone
Domain Details Per Protein
Protein Length Alpha crystallin/Hsp20 domain Alpha crystallin/Small heat shock protein, animal type Heat shock protein beta-8 Heat shock protein beta-8, alpha-crystallin domain (ACD) HSP20-like chaperone
UniProtKB:Q6PFS1 216
UniProtKB:A2BHS1 216
UniProtKB:A2BHS0 145
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations