Gene
slc35b4
- ID
- ZDB-GENE-030131-2457
- Name
- solute carrier family 35 member B4
- Symbol
- slc35b4 Nomenclature History
- Previous Names
-
- fc08c12
- fc29f04
- fi03h11
- wu:fc08c12
- wu:fc29f04
- wu:fi03h11
- zgc:55288 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable UDP-N-acetylglucosamine transmembrane transporter activity and UDP-xylose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in intestinal bulb and notochord. Orthologous to human SLC35B4 (solute carrier family 35 member B4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55288 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR013657 | SLC35B1-4/HUT1 |
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Domain Details Per Protein
| Protein | Length | SLC35B1-4/HUT1 |
|---|---|---|
|
UniProtKB:Q7ZW46
|
331 | |
|
UniProtKB:F1Q9W9
|
331 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc35b4-201
(1)
|
Ensembl | 2,176 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-267N3 | ZFIN Curated Data | |
| Encodes | EST | fc08c12 | ||
| Encodes | EST | fc29f04 | ||
| Encodes | EST | fi03h11 | ||
| Encodes | cDNA | MGC:55288 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_212652 (1) | 2155 nt | ||
| Genomic | GenBank:BX511217 (1) | 149396 nt | ||
| Polypeptide | UniProtKB:F1Q9W9 (1) | 331 aa |
No data available
- Zhang, J., Zhou, Y., Wu, C., Wan, Y., Fang, C., Li, J., Fang, W., Yi, R., Zhu, G., Li, J., Wang, Y. (2018) Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts. Frontiers in endocrinology. 9:756
- Yeh, K.Y., Lai, C.Y., Lin, C.Y., Hsu, C.C., Lo, C.P., Her, G.M. (2017) ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish. Scientific Reports. 7:16362
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Her, G.M., Pai, W.Y., Lai, C.Y., Hsieh, Y.W., and Pang, H.W. (2013) Ubiquitous transcription factor YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 expression. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1831(6):1037-51
- Pai, W.Y., Hsu, C.C., Lai, C.Y., Chang, T.Z., Tsai, Y.L., and Her, G.M. (2013) Cannabinoid receptor 1 promotes hepatic lipid accumulation and lipotoxicity through the induction of SREBP-1c expression in zebrafish. Transgenic Research. 22(4):823-38
- Her, G.M., Hsu, C.C., Hong, J.R., Lai, C.Y., Hsu, M.C., Pang, H.W., Chan, S.K., and Pai, W.Y. (2011) Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio). Biochimica et biophysica acta. Molecular and cell biology of lipids. 1811(9):536-48
- Lindeman, L.C., Andersen, I.S., Reiner, A.H., Li, N., Aanes, H., Ostrup, O., Winata, C., Mathavan, S., Muller, F., Aleström, P., and Collas, P. (2011) Prepatterning of Developmental Gene Expression by Modified Histones before Zygotic Genome Activation. Developmental Cell. 21(6):993-1004
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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