Gene

cav1

ID
ZDB-GENE-030131-2415
Name
caveolin 1
Symbol
cav1 Nomenclature History
Previous Names
  • wu:fc07c04
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Exhibits beta-catenin binding activity. Involved in several processes, including animal organ development; regionalization; and regulation of defense response. Predicted to colocalize with caveola; focal adhesion; and sarcolemma. Is expressed in several structures, including cardiovascular system; ectoderm; integument; lateral line system; and tail bud. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Orthologous to human CAV1 (caveolin 1).
Genome Resources
Note
None
Expression
All Expression Data
20 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cav1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital generalized lipodystrophy type 3 Alliance ?Lipodystrophy, congenital generalized, type 3 612526
primary pulmonary hypertension Alliance Pulmonary hypertension, primary, 3 615343
Lipodystrophy, familial partial, type 7 606721
Associated With cav1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018361 Caveolin, conserved site
Family IPR001612 Caveolin
Family IPR015504 Caveolin-1
Domain Details Per Protein
Protein Length Caveolin Caveolin-1 Caveolin, conserved site
UniProtKB:Q6YLH8 148
UniProtKB:Q6YLH9 181
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations