Gene

aebp1a

ID

ZDB-GENE-030131-2390

Name

AE binding protein 1a

Symbol

aebp1a Nomenclature History

Previous Names

aebp1
fc06f06
si:dkey-24n17.4
wu:fc06f06 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within proteolysis. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome classic-like 2. Orthologous to human AEBP1 (AE binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aebp1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Ehlers-Danlos syndrome classic-like 2	Alliance	Ehlers-Danlos syndrome, classic-like, 2	618000

Associated With aebp1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000421	Coagulation factor 5/8, C-terminal domain
Domain	IPR000834	Peptidase M14, carboxypeptidase A
Family	IPR050753	Peptidase M14 domain-containing protein
Homologous_superfamily	IPR008969	Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily