Gene
aebp1a
- ID
- ZDB-GENE-030131-2390
- Name
- AE binding protein 1a
- Symbol
- aebp1a Nomenclature History
- Previous Names
-
- aebp1
- fc06f06
- si:dkey-24n17.4
- wu:fc06f06 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and metallocarboxypeptidase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; peptide metabolic process; and protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome classic-like 2. Orthologous to human AEBP1 (AE binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ehlers-Danlos syndrome classic-like 2 | Alliance | Ehlers-Danlos syndrome, classic-like, 2 | 618000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000421 | Coagulation factor 5/8, C-terminal domain |
| Domain | IPR000834 | Peptidase M14, carboxypeptidase A |
| Family | IPR050753 | Peptidase M14 domain-containing protein |
| Homologous_superfamily | IPR008969 | Carboxypeptidase-like, regulatory domain superfamily |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Carboxypeptidase-like, regulatory domain superfamily | Coagulation factor 5/8, C-terminal domain | Galactose-binding-like domain superfamily | Peptidase M14, carboxypeptidase A | Peptidase M14 domain-containing protein |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F829
|
1022 |
Interactions and Pathways
No data available
Plasmids
No data available