Gene
kifap3b
- ID
- ZDB-GENE-030131-2219
- Name
- kinesin-associated protein 3b
- Symbol
- kifap3b Nomenclature History
- Previous Names
-
- kifap3
- fb99h08
- wu:fb99h08
- wz7228 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable kinesin binding activity. Predicted to be involved in cilium organization and microtubule-based movement. Predicted to be part of kinesin II complex. Predicted to be active in axoneme and ciliary transition zone. Orthologous to human KIFAP3 (kinesin associated protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9250 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo | Armadillo-like helical | Armadillo-type fold | Kinesin-associated protein 3 |
|---|---|---|---|---|---|
|
UniProtKB:Q1LWL1
|
772 |
1 - 1 of 1
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kifap3b-201
(1)
|
Ensembl | 3,729 nt | ||
| ncRNA |
kifap3b-002
(1)
|
Ensembl | 370 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-218H11 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-92F1 | ZFIN Curated Data | |
| Encodes | EST | fb99h08 | Iovine et al., 2002 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001144045 (1) | 3764 nt | ||
| Genomic | GenBank:BX548024 (2) | 218565 nt | ||
| Polypeptide | UniProtKB:Q1LWL1 (1) | 772 aa |
- Daane, J.M., Blum, N., Lanni, J., Boldt, H., Iovine, M.K., Higdon, C.W., Johnson, S.L., Lovejoy, N.R., Harris, M.P. (2021) Modulation of bioelectric cues in the evolution of flying fishes. Current biology : CB. 31(22):5052-5061.e8
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Shim, H., Kim, J.H., Kim, C.Y., Hwang, S., Kim, H., Yang, S., Lee, J.E., Lee, I. (2016) Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource. Nucleic acids research. 44:9611-9623
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Iovine, M.K., and Johnson, S.L. (2002) A genetic, deletion, physical, and human homology map of the long fin region on zebrafish linkage group 2. Genomics. 79(6):756-759
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