ZFIN is now using GRCz12tu for Genomic Data
Gene
lsg1
- ID
- ZDB-GENE-030131-2184
- Name
- large 60S subunit nuclear export GTPase 1
- Symbol
- lsg1 Nomenclature History
- Previous Names
-
- fb99b06
- wu:fb99b06
- zgc:76988
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in ribosomal subunit export from nucleus. Predicted to act upstream of or within protein transport. Predicted to be located in Cajal body and endoplasmic reticulum. Predicted to be active in cytosol. Is expressed in eye; immature eye; midbrain; neural plate; and segmental plate. Orthologous to human LSG1 (large 60S subunit nuclear export GTPase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6899082 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006073 | GTP binding domain |
| Domain | IPR030378 | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain |
| Family | IPR043358 | Ras GTPase GNL1-like |
| Homologous_superfamily | IPR023179 | GTP-binding protein, orthogonal bundle domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain | GTP binding domain | GTP-binding protein, orthogonal bundle domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Ras GTPase GNL1-like |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NY89 | InterPro | 640 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers