Gene

cfl1

ID
ZDB-GENE-030131-215
Name
cofilin 1
Symbol
cfl1 Nomenclature History
Previous Names
  • cfl2l
  • wu:fb17d06
  • wu:fb18d11
  • wu:fd59f08
  • wu:fj34b08
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have actin binding activity. Involved in several processes, including cilium assembly; determination of heart left/right asymmetry; and gastrulation. Predicted to localize to actin cytoskeleton. Is expressed in several structures, including DEL; blastomere; digestive system; nervous system; and renal system. Orthologous to human CFL1 (cofilin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cfl1 Human Ortholog
No data available
Associated With cfl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002108 Actin-depolymerising factor homology domain
Family IPR017904 ADF/Cofilin
Family IPR027234 Cofilin 1
Homologous_superfamily IPR029006 ADF-H/Gelsolin-like domain superfamily
Domain Details Per Protein
Protein Length Actin-depolymerising factor homology domain ADF/Cofilin ADF-H/Gelsolin-like domain superfamily Cofilin 1
UniProtKB:Q6TH32 165
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cfl polyclonal Goat
  • WB
Thermo Scientific Pierce Protein Research Products
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations