Gene

actn3b

ID

ZDB-GENE-030131-2040

Name

actinin alpha 3b

Symbol

actn3b Nomenclature History

Previous Names

fb95c03
wu:fb95c03
wu:fc11d03
zgc:77243 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have actin binding activity and calcium ion binding activity. Is expressed in several structures, including musculature system; ovary; pharyngeal arch 3-7; post-vent region; and segmental plate. Orthologous to human ACTN3 (actinin alpha 3 (gene/pseudogene)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With actn3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Alpha-actinin-3 deficiency]	617749
		[Sprinting performance]	617749

Associated With actn3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001589	Actinin-type actin-binding domain, conserved site
Domain	IPR001715	Calponin homology domain
Domain	IPR002048	EF-hand domain
Domain	IPR014837	EF-hand, Ca insensitive
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036872	CH domain superfamily
Repeat	IPR002017	Spectrin repeat
Repeat	IPR018159	Spectrin/alpha-actinin

Domain Details Per Protein

Protein	Length	Actinin-type actin-binding domain, conserved site	Calponin homology domain	CH domain superfamily	EF-hand, Ca insensitive	EF-hand domain	EF-hand domain pair	Spectrin/alpha-actinin	Spectrin repeat
UniProtKB:Q8AX99 InterPro	898

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	actn3b-201 (1) Ensembl	Ensembl	4,785 nt	Select Tool
mRNA	actn3b-203 (1) Ensembl	Ensembl	6,222 nt	Select Tool ZFIN BLAST
ncRNA	actn3b-002 (1) Ensembl	Ensembl	432 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations