Gene

actn3b

ID

ZDB-GENE-030131-2040

Name

actinin alpha 3b

Symbol

actn3b Nomenclature History

Previous Names

fb95c03
wu:fb95c03
wu:fc11d03
zgc:77243 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have actin binding activity and calcium ion binding activity. Is expressed in several structures, including musculature system; ovary; pharyngeal arch 3-7; post-vent region; and segmental plate. Orthologous to human ACTN3 (actinin alpha 3 (gene/pseudogene)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With actn3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Alpha-actinin-3 deficiency]	617749
		[Sprinting performance]	617749

Associated With actn3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001589	Actinin-type actin-binding domain, conserved site
Domain	IPR001715	Calponin homology domain
Domain	IPR002048	EF-hand domain
Domain	IPR014837	EF-hand, Ca insensitive
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036872	CH domain superfamily
Repeat	IPR002017	Spectrin repeat
Repeat	IPR018159	Spectrin/alpha-actinin

Domain Details Per Protein

Protein	Length	Actinin-type actin-binding domain, conserved site	Calponin homology domain	CH domain superfamily	EF-hand, Ca insensitive	EF-hand domain	EF-hand domain pair	Spectrin/alpha-actinin	Spectrin repeat
UniProtKB:Q8AX99 InterPro	898

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	actn3b-201 (1) Ensembl	Ensembl	4,785 nt	Select Tool ZFIN BLAST
mRNA	actn3b-203 (1) Ensembl	Ensembl	6,222 nt	Select Tool ZFIN BLAST
ncRNA	actn3b-002 (1) Ensembl	Ensembl	432 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations