ZFIN is now using GRCz12tu for Genomic Data
Gene
marcksb
- ID
- ZDB-GENE-030131-1921
- Name
- myristoylated alanine-rich protein kinase C substrate b
- Symbol
- marcksb Nomenclature History
- Previous Names
-
- macs (1)
- marcks
- wu:fb55c06
- wu:fb92d04
- wu:fc19b04
- wu:fc44a10
- zgc:110235
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable actin filament binding activity. Involved in positive regulation of BMP secretion. Acts upstream of or within several processes, including gastrulation; retina layer formation; and skeletal muscle cell differentiation. Predicted to be located in membrane. Predicted to be active in actin filament bundle; cytoplasm; and plasma membrane. Is expressed in several structures, including nervous system; neural plate; neural rod; neural tube; and neuroectoderm. Human ortholog(s) of this gene implicated in Lynch syndrome. Orthologous to human MARCKS (myristoylated alanine rich protein kinase C substrate).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903275 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002101 | Myristoylated alanine-rich C-kinase substrate MARCKS |
Domain Details Per Protein
| Protein | Additional Resources | Length | Myristoylated alanine-rich C-kinase substrate MARCKS |
|---|---|---|---|
| UniProtKB:F6NXD5 | InterPro | 227 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
marcksb-201
(1)
|
Ensembl | 1,919 nt | ||
| mRNA |
marcksb-203
(1)
|
Ensembl | 3,771 nt | ||
| ncRNA |
marcksb-002
(1)
|
Ensembl | 317 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers