ZFIN is now using GRCz12tu for Genomic Data
Gene
ewsr1b
- ID
- ZDB-GENE-030131-1600
- Name
- EWS RNA-binding protein 1b
- Symbol
- ewsr1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz11
- Annotation Status
- Unknown
- Description
- Predicted to enable RNA binding activity and transcription coregulator activity. Predicted to be active in nucleus. Is expressed in fin bud; gut; nervous system; and trunk. Human ortholog(s) of this gene implicated in Ewing sarcoma. Orthologous to human EWSR1 (EWS RNA binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Azuma et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ewing sarcoma | Alliance | Ewing sarcoma | 612219 |
| Ewing sarcoma | Alliance | Neuroepithelioma | 612219 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR001876 | Zinc finger, RanBP2-type |
| Family | IPR034870 | TAF15/EWS/TLS family |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR036443 | Zinc finger, RanBP2-type superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | TAF15/EWS/TLS family | Zinc finger, RanBP2-type | Zinc finger, RanBP2-type superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q803E3 | InterPro | 578 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ewsr1b-201
(1)
|
Ensembl | 2,083 nt | ||
| mRNA |
ewsr1b-202
(1)
|
Ensembl | 2,441 nt | ||
| mRNA |
ewsr1b-204
(1)
|
Ensembl | 897 nt | ||
| ncRNA |
ewsr1b-003
(1)
|
Ensembl | 1,207 nt | ||
| ncRNA |
ewsr1b-005
(1)
|
Ensembl | 780 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers