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ZIRC
ZFIN ID: ZDB-GENE-030131-1565
Gene Name: DEAD-box helicase 3 X-linked a
Gene Symbol: ddx3xa    Nomenclature History

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Previous Names: ddx3, ddx3a, fb74g09, wu:fb74g09, zgc:158804

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and RNA helicase activity. Predicted to be involved in cell differentiation and gamete generation. Predicted to localize to the P granule and nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human DDX3X (DEAD-box helicase 3 X-linked) and DDX3Y (DEAD-box helicase 3 Y-linked).
Genome Resources: Alliance (1),  Gene:566947 (1),  Ensembl(GRCz11):ENSDARG00000020573 (2)
GENE EXPRESSION
All Expression Data: Table 1 from Mueller et al., 2010
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026928Tg Transgenic Insertion Unknown Unknown DNA
sa13318 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21526 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38750 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ddx3xa N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ddx3xa HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Mental retardation, X-linked 102 300958
    DISEASE ASSOCIATED WITH ddx3xa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ddx3xa-201 (1)    Ensembl 5007
    ddx3xa-202 (1)    Ensembl 454
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ddx3xa No data available
    MARKER RELATIONSHIPS
    ddx3xa Contained in: [BAC] DKEY-216E24 (1) (order this)
    ddx3xa Encodes: [EST] fb74g09
    [cDNA] MGC:158804 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001126423 (1) 5007 bp
    Genomic GenBank:BX545856 (1) 209295 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A2RV38 (1) 709 aa
    Sequence Clusters UniGene:104653 (1)
    Sequence Information (all 45)
    ORTHOLOGY for ddx3xa ( Chr: 9 )
    CITATIONS (29)